DanceTherParkinsonV1, Main, Exploration, bibRecord, 000240

Serotonin and Dopamine: Unifying Affective, Activational, and Decision Functions

Identifieur interne : 000240 ( Main/Exploration ); précédent : 000239; suivant : 000241

Serotonin and Dopamine: Unifying Affective, Activational, and Decision Functions

Auteurs : Roshan Cools [Pays-Bas] ; Kae Nakamura [Japon] ; Nathaniel D. Daw [États-Unis]

Source :

Neuropsychopharmacology [ 0893-133X ] ; 2010.

RBID : PMC:3055512

Abstract

Serotonin, like dopamine (DA), has long been implicated in adaptive behavior, including decision making and reinforcement learning. However, although the two neuromodulators are tightly related and have a similar degree of functional importance, compared with DA, we have a much less specific understanding about the mechanisms by which serotonin affects behavior. Here, we draw on recent work on computational models of dopaminergic function to suggest a framework by which many of the seemingly diverse functions associated with both DA and serotonin—comprising both affective and activational ones, as well as a number of other functions not overtly related to either—can be seen as consequences of a single root mechanism.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055512

DOI: 10.1038/npp.2010.121
PubMed: 20736991
PubMed Central: 3055512

Affiliations:

Japon, Pays-Bas, États-Unis

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Danse-thérapie et Parkinson

Serotonin and Dopamine: Unifying Affective, Activational, and Decision Functions

Serotonin and Dopamine: Unifying Affective, Activational, and Decision Functions

Source :

Abstract

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